To configure routing or add route

You can use route command to configure routing. Syntax is as follows:
route add net {network-address} netmask {subnet} {router-address}

Let us assume your router address is 192.168.1.254 and network ID is 192.168.1.0/24, then you can type route command as follows:
# route add net 192.168.1.0 netmask 255.255.255.0 192.168.1.254

OR

To add a default route:
# route add default 192.168.1.254

Verify that (display) routing table is updated (display routing table):
# netstat -nr

Test it i.e. try to ping or send nslookup request:
# ping mycorp.com

To flush all routing entries use command [quite handy to clean your gordian knot ;)] :
# route -f

However if I reboot HPUX box then above routing entries gets removed. To pick up your setting upon each reboot your need to configure Routes in HPUX networking configuration file - /etc/rc.config.d/netconf. To add default router/gateway 192.168.1.254:
# vi /etc/rc.config.d/netconf

Add or modify following entries

ROUTE_DESTINATION[0]="default"
ROUTE_MASK[0]=""
ROUTE_GATEWAY[0]="192.168.1.254"
ROUTE_COUNT[0]="1"
ROUTE_ARGS[0]=""

Reboot HP-UX system/server to take effect
# shutdown -ry 0 Someone might attack on your system. You can drop attacker IP using IPtables. However, you can use route command to null route unwanted traffic. A null route (also called as blackhole route) is a network route or kernel routing table entry that goes nowhere. Matching packets are dropped (ignored) rather than forwarded, acting as a kind of very limited firewall. The act of using null routes is often called blackhole filtering.

You can nullroute (like some time ISP do prevent your network device from sending any data to a remote system.) stopping various attacks coming from a single IP (read as spammers or hackers):

Nullroute IP using route command

Suppose that bad IP is 65.21.34.4, type following command at shell:

# route add 65.21.34.4 gw 127.0.0.1 lo

You can verify it with following command:
# netstat -nr
OR
# route -n
You can also use reject target (thanks to Gabriele):
# route add -host IP-ADDRESS reject
# route add -host 64.1.2.3 reject

To confirm the null routing status, use ip command as follows:
# ip route get 64.1.2.3
Output:

RTNETLINK answers: Network is unreachable

Drop entire subnet 192.67.16.0/24:
# route add -net 192.67.16.0/24 gw 127.0.0.1 lo
You can also use ip command to null route network or ip, enter:
# ip route add blackhole 202.54.5.2/29
# route -n

How do I remove null routing? How do I remove blocked IP address?

Simple use router delete command,
# route delete 65.21.34.4
This is cool, as you do not have to play with iptables rules.

Q. How do I setup default gateway with a route command?

A. route command show and/or manipulate the IP routing table under Linux and UNIX oses.

Route manipulates the kernel's IP routing tables. Its primary use is to set up static routes to specific hosts or networks via an interface after it has been configured with the ifconfig program. When the add or del options are used, route modifies the routing tables. Without these options, route displays the current contents of the routing tables.

Display default route

Following three-command display the current routing table:
# route
Output:

Kernel IP routing table
Destination     Gateway         Genmask         Flags Metric Ref    Use Iface
192.168.1.0     *               255.255.255.0   U     0      0        0 ra0
default         dsl-router      0.0.0.0         UG    0      0        0 ra0

$ /sbin/route
Output:

Kernel IP routing table
Destination     Gateway         Genmask         Flags Metric Ref    Use Iface
191.255.255.0   *               255.255.255.0   U     0      0        0 eth0
169.254.0.0     *               255.255.0.0     U     0      0        0 eth0
default         191.255.255.1   0.0.0.0         UG    0      0        0 eth0

You can use -n option, to display numerical addresses instead of trying to determine symbolic host names (via dns or /etc/hosts file). This is useful if you are trying to determine why the route to your nameserver has vanished.$ /sbin/route -nOutput:

Kernel IP routing table
Destination     Gateway         Genmask         Flags Metric Ref    Use Iface
191.255.255.0   0.0.0.0         255.255.255.0   U     0      0        0 venet0
169.254.0.0     0.0.0.0         255.255.0.0     U     0      0        0 venet0
0.0.0.0         191.255.255.1   0.0.0.0         UG    0      0        0 venet0

Please note that a destionation entry 0.0.0.0 (or default) is the default gatway. In above example 191.255.255.1 is a default gatway.

Add / setup a new route

The syntax is as follows:
route add default gw {IP-ADDRESS} {INTERFACE-NAME}

Where,

• IP-ADDRESS: Specify router IP address
• INTERFACE-NAME: Specify interface name such as eth0

For example if your router IP address is 192.168.1.254 type the following command as the root user:
# route add default gw 192.168.1.254 eth0OR use hostname such as dsl-router:# route add default gw dsl-router eth0

Setting route using GUI tools/command under Linux

If you find above command hard to use, consider using GUI tools. If your are using Red Hat/CentOS/Fedora core Linux type following command:# redhat-config-networkOR If you are using other Linux distribution use command:# network-admin